Preclinical activity of the novel B‐cell‐specific Moloney murine leukemia virus integration site 1 inhibitor PTC‐209 in acute myeloid leukemia: Implications for leukemia therapy

Curing patients with acute myeloid leukemia (AML) remains a therapeutic challenge. The polycomb complex protein B‐cell‐specific Moloney murine leukemia virus integration site 1 (BMI‐1) is required for the self‐renewal and maintenance of leukemia stem cells. We investigated the prognostic significanc...

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Detalles Bibliográficos
Autores principales: Nishida, Yuki, Maeda, Aya, Chachad, Dhruv, Ishizawa, Jo, Qiu, Yi Hua, Kornblau, Steven M., Kimura, Shinya, Andreeff, Michael, Kojima, Kensuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714665/
https://www.ncbi.nlm.nih.gov/pubmed/26450753
http://dx.doi.org/10.1111/cas.12833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714665/
https://www.ncbi.nlm.nih.gov/pubmed/26450753
http://dx.doi.org/10.1111/cas.12833

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