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Preclinical activity of the novel B‐cell‐specific Moloney murine leukemia virus integration site 1 inhibitor PTC‐209 in acute myeloid leukemia: Implications for leukemia therapy
Curing patients with acute myeloid leukemia (AML) remains a therapeutic challenge. The polycomb complex protein B‐cell‐specific Moloney murine leukemia virus integration site 1 (BMI‐1) is required for the self‐renewal and maintenance of leukemia stem cells. We investigated the prognostic significanc...
Autores principales: | Nishida, Yuki, Maeda, Aya, Chachad, Dhruv, Ishizawa, Jo, Qiu, Yi Hua, Kornblau, Steven M., Kimura, Shinya, Andreeff, Michael, Kojima, Kensuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714665/ https://www.ncbi.nlm.nih.gov/pubmed/26450753 http://dx.doi.org/10.1111/cas.12833 |
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