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Non‐autonomous overgrowth by oncogenic niche cells: Cellular cooperation and competition in tumorigenesis

Tumor progression is classically viewed as the Darwinian evolution of subclones that sequentially acquire genetic mutations and autonomously overproliferate. However, growing evidence suggests that tumor microenvironment and subclone heterogeneity contribute to non‐autonomous tumor progression. Rece...

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Detalles Bibliográficos
Autores principales: Enomoto, Masato, Vaughen, John, Igaki, Tatsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714670/
https://www.ncbi.nlm.nih.gov/pubmed/26362609
http://dx.doi.org/10.1111/cas.12816