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Deletion status of p16 in effusion smear preparation correlates with that of underlying malignant pleural mesothelioma tissue

Differentiating malignant pleural mesothelioma (MPM) cells morphologically from reactive mesothelial hyperplasia cells is problematic. Homozygous deletion (HD) of p16 (CDKN2A), detected by FISH, is a good marker of malignancy and is useful to differentiate between these cells. However, the correlati...

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Detalles Bibliográficos
Autores principales: Hida, Tomoyuki, Matsumoto, Shinji, Hamasaki, Makoto, Kawahara, Kunimitsu, Tsujimura, Tohru, Hiroshima, Kenzo, Kamei, Toshiaki, Taguchi, Kenichi, Iwasaki, Akinori, Oda, Yoshinao, Honda, Hiroshi, Nabeshima, Kazuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714681/
https://www.ncbi.nlm.nih.gov/pubmed/26291840
http://dx.doi.org/10.1111/cas.12769