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Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK‐A (y) and Apc mutant Min mice

Obesity is a risk factor for colorectal cancer. The accumulation of abdominal fat tissue causes abundant reactive oxygen species production through the activation of NADPH oxidase due to excessive insulin stimulation. The enzyme NADPH oxidase catalyzes the production of reactive oxygen species and e...

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Detalles Bibliográficos
Autores principales: Komiya, Masami, Fujii, Gen, Miyamoto, Shingo, Takahashi, Mami, Ishigamori, Rikako, Onuma, Wakana, Ishino, Kousuke, Totsuka, Yukari, Fujimoto, Kyoko, Mutoh, Michihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714685/
https://www.ncbi.nlm.nih.gov/pubmed/26310859
http://dx.doi.org/10.1111/cas.12801