A clinically attainable dose of L‐asparaginase targets glutamine addiction in lymphoid cell lines

L‐asparaginase (L‐ASNase) is an important branch of chemotherapy for acute lymphoblastic leukemia (ALL) and some types of non‐Hodgkin's lymphoma, including natural killer (NK)‐cell lymphoma. Although it mediates hydrolysis of asparagine (Asn) and glutamine (Gln), which are variably required for...

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Detalles Bibliográficos
Autores principales: Sugimoto, Koichi, Suzuki, Hiroshi I., Fujimura, Tsutomu, Ono, Asami, Kaga, Naoko, Isobe, Yasushi, Sasaki, Makoto, Taka, Hikari, Miyazono, Kohei, Komatsu, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714686/
https://www.ncbi.nlm.nih.gov/pubmed/26331698
http://dx.doi.org/10.1111/cas.12807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714686/
https://www.ncbi.nlm.nih.gov/pubmed/26331698
http://dx.doi.org/10.1111/cas.12807

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