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Retinoid X receptor α enhances human cholangiocarcinoma growth through simultaneous activation of Wnt/β‐catenin and nuclear factor‐κB pathways

Retinoid X receptor α (RXRα) plays important roles in the malignancy of several cancers such as human prostate tumor, breast cancer, and thyroid tumor. However, its exact functions and molecular mechanisms in cholangiocarcinoma (CCA), a chemoresistant carcinoma with poor prognosis, remain unclear. I...

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Detalles Bibliográficos
Autores principales: Huang, Gui‐Li, Zhang, Wei, Ren, Hong‐Yue, Shen, Xue‐Ying, Chen, Qing‐Xi, Shen, Dong‐Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714697/
https://www.ncbi.nlm.nih.gov/pubmed/26310932
http://dx.doi.org/10.1111/cas.12802