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Transforming growth factor‐β signaling enhancement by long‐term exposure to hypoxia in a tumor microenvironment composed of Lewis lung carcinoma cells
Transforming growth factor‐β (TGF‐β) is a potent growth inhibitor in normal epithelial cells. However, a number of malignant tumors produce excessive amounts of TGF‐β, which affects the tumor‐associated microenvironment by furthering the progression of tumorigenicity. Although it is known that the t...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714699/ https://www.ncbi.nlm.nih.gov/pubmed/26296946 http://dx.doi.org/10.1111/cas.12773 |