Excessive cocaine use results from decreased phasic dopamine signaling in the striatum

Drug addiction is a neuropsychiatric disorder marked by escalating drug use. Dopamine neurotransmission in the ventromedial striatum (VMS) mediates acute reinforcing effects of abused drugs, but with protracted use the dorsolateral striatum (DLS) is thought to assume control over drug seeking. We me...

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Detalles Bibliográficos
Autores principales: Willuhn, Ingo, Burgeno, Lauren M., Groblewski, Peter A., Phillips, Paul E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714770/
https://www.ncbi.nlm.nih.gov/pubmed/24705184
http://dx.doi.org/10.1038/nn.3694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714770/
https://www.ncbi.nlm.nih.gov/pubmed/24705184
http://dx.doi.org/10.1038/nn.3694

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