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Mutations of the Calcium Channel Gene cacophony Suppress Seizures in Drosophila
Bang sensitive (BS) Drosophila mutants display characteristic seizure-like phenotypes resembling, in some aspects, those of human seizure disorders such as epilepsy. The BS mutant para(bss1), caused by a gain-of-function mutation of the voltage-gated Na(+) channel gene, is extremely seizure-sensitiv...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714812/ https://www.ncbi.nlm.nih.gov/pubmed/26771829 http://dx.doi.org/10.1371/journal.pgen.1005784 |