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Golgi-Resident GTPase Rab30 Promotes the Biogenesis of Pathogen-Containing Autophagosomes

Autophagy acts as a host-defense system against pathogenic microorganisms such as Group A Streptococcus (GAS). Autophagy is a membrane-mediated degradation system that is regulated by intracellular membrane trafficking regulators, including small GTPase Rab proteins. Here, we identified Rab30 as a n...

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Detalles Bibliográficos
Autores principales: Oda, Seiichiro, Nozawa, Takashi, Nozawa-Minowa, Atsuko, Tanaka, Misako, Aikawa, Chihiro, Harada, Hiroyuki, Nakagawa, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714835/
https://www.ncbi.nlm.nih.gov/pubmed/26771875
http://dx.doi.org/10.1371/journal.pone.0147061