Cargando…

Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease

Impaired function of NPC1 or NPC2 lysosomal proteins leads to the intracellular accumulation of unesterified cholesterol, the primary defect underlying Niemann-Pick type C (NPC) disease. In addition, glycosphingolipids (GSLs) accumulate in lysosomes as well. Intralysosomal lipid accumulation trigger...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marques, André R. A., Gabriel, Tanit L., Aten, Jan, van Roomen, Cindy P. A. A., Ottenhoff, Roelof, Claessen, Nike, Alfonso, Pilar, Irún, Pilar, Giraldo, Pilar, Aerts, Johannes M. F. G., van Eijk, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714856/ https://www.ncbi.nlm.nih.gov/pubmed/26771826 http://dx.doi.org/10.1371/journal.pone.0147208

Ejemplares similares

GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice
por: van der Lienden, Martijn J. C., et al.
Publicado: (2021)

Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice
por: Marques, André R. A., et al.
Publicado: (2015)

Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival
por: Gabriel, Tanit L., et al.
Publicado: (2017)

Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain
por: van Rooden, Eva J., et al.
Publicado: (2018)

Assessment of plasma chitotriosidase activity, CCL18/PARC concentration and NP-C suspicion index in the diagnosis of Niemann-Pick disease type C: a prospective observational study
por: De Castro-Orós, Isabel, et al.
Publicado: (2017)

Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases
por: Marques, André R. A., et al.
Publicado: (2016)

Inhibition of Intermediate-Conductance Calcium-Activated K Channel (KCa3.1) and Fibroblast Mitogenesis by α-Linolenic Acid and Alterations of Channel Expression in the Lysosomal Storage Disorders, Fabry Disease, and Niemann Pick C
por: Oliván-Viguera, Aida, et al.
Publicado: (2017)

Correction of Liver Steatosis by a Hydrophobic Iminosugar Modulating Glycosphingolipids Metabolism
por: Lombardo, Elisa, et al.
Publicado: (2012)

Reducing Glycosphingolipid Content in Adipose Tissue of Obese Mice Restores Insulin Sensitivity, Adipogenesis and Reduces Inflammation
por: van Eijk, Marco, et al.
Publicado: (2009)

Niemann-Pick disease type C
por: Vanier, Marie T
Publicado: (2010)

Stem Cells and Niemann Pick Disease
por: Andolina, Marino
Publicado: (2014)

Stem Cells in Niemann-Pick Disease
por: Kim, Sun-Jung, et al.
Publicado: (2008)

Niemann-Pick disease and platelet dysfunction
Publicado: (2012)

Tolerance of chronic HDACi treatment for neurological, visceral and lung Niemann-Pick Type C disease in mice
por: Alam, Md. Suhail, et al.
Publicado: (2018)

Photomyogenic response in Niemann–Pick type C: a case report
por: Bour, A., et al.
Publicado: (2010)

Clear Cell Chondrosarcoma in Association With Niemann-Pick Disease
por: Srikanth, K. N., et al.
Publicado: (2005)

Intracerebroventricular Treatment with 2-Hydroxypropyl-β-Cyclodextrin Decreased Cerebellar and Hepatic Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Expression in Niemann–Pick Disease Type C Model Mice
por: Fukaura, Madoka, et al.
Publicado: (2021)

A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity
por: Tol, Marc J., et al.
Publicado: (2016)

Lysosomal and Mitochondrial Liaisons in Niemann-Pick Disease
por: Torres, Sandra, et al.
Publicado: (2017)

Niemann-Pick Disease: An Approach for Diagnosis in Adulthood
por: Patiño-Escobar, Bonell, et al.
Publicado: (2019)

Immune dysfunction in Niemann‐Pick disease type C
por: Platt, Nick, et al.
Publicado: (2015)

Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes
por: Herrera Moro Chao, Daniela, et al.
Publicado: (2015)

Involvement of the Choroid Plexus in the Pathogenesis of Niemann-Pick Disease Type C
por: Van Hoecke, Lien, et al.
Publicado: (2021)

Ataxia, dystonia and myoclonus in adult patients with Niemann-Pick type C
por: Koens, L. H., et al.
Publicado: (2016)

The prognostic value of Niemann-Pick C1-like protein 1 and Niemann-Pick disease type C2 in hepatocellular carcinoma
por: Chen, Ke-Ji, et al.
Publicado: (2018)

Clinical disease characteristics of patients with Niemann-Pick Disease Type C: findings from the International Niemann-Pick Disease Registry (INPDR)
por: Bolton, Shaun C., et al.
Publicado: (2022)

Anesthetic Management in a Child With Niemann-Pick Disease
por: Espahbodi, Ebrahim, et al.
Publicado: (2016)

Niemann-Pick Disease: An Underdiagnosed Lysosomal Storage Disorder
por: Panigrahi, Inusha, et al.
Publicado: (2019)

A calcium message for Niemann-Pick type C
por: Cologna, Stephanie M.
Publicado: (2019)

Treatment trials in Niemann-Pick type C disease
por: Sitarska, Dominika, et al.
Publicado: (2021)

Retinal axonal degeneration in Niemann–Pick type C disease
por: Havla, Joachim, et al.
Publicado: (2020)

Efficacy and ototoxicity of different cyclodextrins in Niemann–Pick C disease
por: Davidson, Cristin D., et al.
Publicado: (2016)

Genome sequencing in a case of Niemann–Pick type C
por: Dougherty, Max, et al.
Publicado: (2016)

Niemann–Pick disease type C: introduction and main clinical features
por: Burlina, A.
Publicado: (2014)

Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann–Pick diseases
por: Schultz, Mark L., et al.
Publicado: (2019)

Niemann Pick C disease: lessons from zebrafish development
Publicado: (2011)

Intestinal and Hepatic Niemann-Pick C1-Like 1
por: Park, Sung-Woo
Publicado: (2013)

Complement is dispensable for neurodegeneration in Niemann-Pick disease type C
por: Lopez, Manuel E, et al.
Publicado: (2012)

Niemann-Pick Diseases: The Largest Iranian Cohort with Genetic Analysis
por: Hashemian, Somayyeh, et al.
Publicado: (2019)

Mechanistic convergence and shared therapeutic targets in Niemann‐Pick disease
por: Colaco, Alexandria, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_q016bdnm6m6sijghmsiphgsbn6