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The p70S6K Specific Inhibitor PF-4708671 Impedes Non-Small Cell Lung Cancer Growth
BACKGROUND: As a serine/threonine protein kinase, p70S6K plays an important role in tumor cells. Evidence has revealed overexpression of p70S6K and phosphorylated p70S6K (p-p70S6K) in various tumor tissues, with these proteins identified as independent prognostic markers in non-small cell lung cance...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714881/ https://www.ncbi.nlm.nih.gov/pubmed/26771549 http://dx.doi.org/10.1371/journal.pone.0147185 |