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The p70S6K Specific Inhibitor PF-4708671 Impedes Non-Small Cell Lung Cancer Growth

BACKGROUND: As a serine/threonine protein kinase, p70S6K plays an important role in tumor cells. Evidence has revealed overexpression of p70S6K and phosphorylated p70S6K (p-p70S6K) in various tumor tissues, with these proteins identified as independent prognostic markers in non-small cell lung cance...

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Detalles Bibliográficos
Autores principales:	Qiu, Zhi-Xin, Sun, Rong-Fei, Mo, Xian-Ming, Li, Wei-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714881/ https://www.ncbi.nlm.nih.gov/pubmed/26771549 http://dx.doi.org/10.1371/journal.pone.0147185

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