Orally Active and Selective Tubulin Inhibitors as Anti-Trypanosome Agents

OBJECTIVES: There is an urgent need to develop a safe, effective, orally active, and inexpensive therapy for African trypanosomiasis due to the drawbacks of current drugs. Selective tubulin inhibitors have the potential to be promising drug candidates for the treatment of this disease, which is base...

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Detalles Bibliográficos
Autores principales: Nanavaty, Vishal, Lama, Rati, Sandhu, Ranjodh, Zhong, Bo, Kulman, Daniel, Bobba, Viharika, Zhao, Anran, Li, Bibo, Su, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714897/
https://www.ncbi.nlm.nih.gov/pubmed/26771307
http://dx.doi.org/10.1371/journal.pone.0146289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714897/
https://www.ncbi.nlm.nih.gov/pubmed/26771307
http://dx.doi.org/10.1371/journal.pone.0146289

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