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Orally Active and Selective Tubulin Inhibitors as Anti-Trypanosome Agents
OBJECTIVES: There is an urgent need to develop a safe, effective, orally active, and inexpensive therapy for African trypanosomiasis due to the drawbacks of current drugs. Selective tubulin inhibitors have the potential to be promising drug candidates for the treatment of this disease, which is base...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714897/ https://www.ncbi.nlm.nih.gov/pubmed/26771307 http://dx.doi.org/10.1371/journal.pone.0146289 |