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Targeted scVEGF/(177)Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy

BACKGROUND: scVEGF/(177)Lu is a novel radiopharmaceutical targeted by recombinant single-chain (sc) derivative of vascular endothelial growth factor (VEGF) that binds to and is internalized by vascular endothelial growth factor receptors (VEGFR). scVEGF/(177)Lu potential as adjuvant and neoadjuvant...

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Detalles Bibliográficos
Autores principales: Rusckowski, Mary, Wang, Yuzhen, Blankenberg, Francis G., Levashova, Zoia, Backer, Marina V., Backer, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715132/
https://www.ncbi.nlm.nih.gov/pubmed/26780081
http://dx.doi.org/10.1186/s13550-016-0163-1