Cargando…

Role of WWOX and NF-κB in lung cancer progression

It is generally agreed that the pro-inflammatory, pro-survival transcription factor NF-κB is a tumor promoter. Tumor necrosis factor alpha (TNF-α or TNF) mediates NF-κB activation. Tumor suppressor WWOX (FOR or WOX1) is a downstream effector of the TNF signaling. Thus, activation of both WWOX (FOR o...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Szu-Jung, Huang, Shenq-Shyang, Chang, Nan-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715152/
https://www.ncbi.nlm.nih.gov/pubmed/27234396
http://dx.doi.org/10.1186/2213-0802-1-15