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Dipeptidyl Peptidase 4 Distribution in the Human Respiratory Tract: Implications for the Middle East Respiratory Syndrome

Dipeptidyl peptidase 4 (DPP4, CD26), a type II transmembrane ectopeptidase, is the receptor for the Middle Eastern respiratory syndrome coronavirus (MERS-CoV). MERS emerged in 2012 and has a high mortality associated with severe lung disease. A lack of autopsy studies from MERS fatalities has hinder...

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Detalles Bibliográficos
Autores principales: Meyerholz, David K., Lambertz, Allyn M., McCray, Paul B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715219/
https://www.ncbi.nlm.nih.gov/pubmed/26597880
http://dx.doi.org/10.1016/j.ajpath.2015.09.014