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The clinical trial landscape in oncology and connectivity of somatic mutational profiles to targeted therapies

BACKGROUND: Precision medicine in oncology relies on rapid associations between patient-specific variations and targeted therapeutic efficacy. Due to the advancement of genomic analysis, a vast literature characterizing cancer-associated molecular aberrations and relative therapeutic relevance has b...

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Detalles Bibliográficos
Autores principales: Patterson, Sara E., Liu, Rangjiao, Statz, Cara M., Durkin, Daniel, Lakshminarayana, Anuradha, Mockus, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715272/
https://www.ncbi.nlm.nih.gov/pubmed/26772741
http://dx.doi.org/10.1186/s40246-016-0061-7