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The clinical trial landscape in oncology and connectivity of somatic mutational profiles to targeted therapies
BACKGROUND: Precision medicine in oncology relies on rapid associations between patient-specific variations and targeted therapeutic efficacy. Due to the advancement of genomic analysis, a vast literature characterizing cancer-associated molecular aberrations and relative therapeutic relevance has b...
Autores principales: | Patterson, Sara E., Liu, Rangjiao, Statz, Cara M., Durkin, Daniel, Lakshminarayana, Anuradha, Mockus, Susan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715272/ https://www.ncbi.nlm.nih.gov/pubmed/26772741 http://dx.doi.org/10.1186/s40246-016-0061-7 |
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