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Functional analysis of monoclonal antibodies against the Plasmodium falciparum PfEMP1-VarO adhesin
BACKGROUND: Rosetting, namely the capacity of the Plasmodium falciparum-infected red blood cells to bind uninfected RBCs, is commonly observed in African children with severe malaria. Rosetting results from specific interactions between a subset of variant P. falciparum erythrocyte membrane protein...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715314/ https://www.ncbi.nlm.nih.gov/pubmed/26772184 http://dx.doi.org/10.1186/s12936-015-1016-5 |