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Functional analysis of monoclonal antibodies against the Plasmodium falciparum PfEMP1-VarO adhesin

BACKGROUND: Rosetting, namely the capacity of the Plasmodium falciparum-infected red blood cells to bind uninfected RBCs, is commonly observed in African children with severe malaria. Rosetting results from specific interactions between a subset of variant P. falciparum erythrocyte membrane protein...

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Detalles Bibliográficos
Autores principales: Guillotte, Micheline, Nato, Farida, Juillerat, Alexandre, Hessel, Audrey, Marchand, Françoise, Lewit-Bentley, Anita, Bentley, Graham A., Vigan-Womas, Inès, Mercereau-Puijalon, Odile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715314/
https://www.ncbi.nlm.nih.gov/pubmed/26772184
http://dx.doi.org/10.1186/s12936-015-1016-5