A computational method for genotype calling in family-based sequencing data

BACKGROUND: As sequencing technologies can help researchers detect common and rare variants across the human genome in many individuals, it is known that jointly calling genotypes across multiple individuals based on linkage disequilibrium (LD) can facilitate the analysis of low to modest coverage s...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Lun-Ching, Li, Bingshan, Fang, Zhou, Vrieze, Scott, McGue, Matt, Iacono, William G., Tseng, George C., Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715317/
https://www.ncbi.nlm.nih.gov/pubmed/26772743
http://dx.doi.org/10.1186/s12859-016-0880-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715317/
https://www.ncbi.nlm.nih.gov/pubmed/26772743
http://dx.doi.org/10.1186/s12859-016-0880-5

Ejemplares similares