Facilitation of axon outgrowth via a Wnt5a-CaMKK-CaMKIα pathway during neuronal polarization

BACKGROUND: Wnt5a, originally identified as a guidance cue for commissural axons, activates a non-canonical pathway critical for cortical axonal morphogenesis. The molecular signaling cascade underlying this event remains obscure. RESULTS: Through Ca(2+) imaging in acute embryonic cortical slices, w...

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Detalles Bibliográficos
Autores principales: Horigane, Shin-ichiro, Ageta-Ishihara, Natsumi, Kamijo, Satoshi, Fujii, Hajime, Okamura, Michiko, Kinoshita, Makoto, Takemoto-Kimura, Sayaka, Bito, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715351/
https://www.ncbi.nlm.nih.gov/pubmed/26772170
http://dx.doi.org/10.1186/s13041-016-0189-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715351/
https://www.ncbi.nlm.nih.gov/pubmed/26772170
http://dx.doi.org/10.1186/s13041-016-0189-3

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