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Facilitation of axon outgrowth via a Wnt5a-CaMKK-CaMKIα pathway during neuronal polarization
BACKGROUND: Wnt5a, originally identified as a guidance cue for commissural axons, activates a non-canonical pathway critical for cortical axonal morphogenesis. The molecular signaling cascade underlying this event remains obscure. RESULTS: Through Ca(2+) imaging in acute embryonic cortical slices, w...
Autores principales: | Horigane, Shin-ichiro, Ageta-Ishihara, Natsumi, Kamijo, Satoshi, Fujii, Hajime, Okamura, Michiko, Kinoshita, Makoto, Takemoto-Kimura, Sayaka, Bito, Haruhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715351/ https://www.ncbi.nlm.nih.gov/pubmed/26772170 http://dx.doi.org/10.1186/s13041-016-0189-3 |
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