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Leucine‐rich repeat kinase 2 interacts with p21‐activated kinase 6 to control neurite complexity in mammalian brain

Leucine‐rich repeat kinase 2 (LRRK2) is a causative gene for Parkinson's disease, but the physiological function and the mechanism(s) by which the cellular activity of LRRK2 is regulated are poorly understood. Here, we identified p21‐activated kinase 6 (PAK6) as a novel interactor of the GTPase...

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Detalles Bibliográficos
Autores principales: Civiero, Laura, Cirnaru, Maria Daniela, Beilina, Alexandra, Rodella, Umberto, Russo, Isabella, Belluzzi, Elisa, Lobbestael, Evy, Reyniers, Lauran, Hondhamuni, Geshanthi, Lewis, Patrick A., Van den Haute, Chris, Baekelandt, Veerle, Bandopadhyay, Rina, Bubacco, Luigi, Piccoli, Giovanni, Cookson, Mark R., Taymans, Jean‐Marc, Greggio, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715492/
https://www.ncbi.nlm.nih.gov/pubmed/26375402
http://dx.doi.org/10.1111/jnc.13369