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Putative Prostate Cancer Risk SNP in an Androgen Receptor‐Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in Androgen Receptor Target Sites

Genome‐wide association studies have identified genomic loci, whose single‐nucleotide polymorphisms (SNPs) predispose to prostate cancer (PCa). However, the mechanisms of most of these variants are largely unknown. We integrated chromatin‐immunoprecipitation‐coupled sequencing and microarray express...

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Detalles Bibliográficos
Autores principales: Bu, Huajie, Narisu, Narisu, Schlick, Bettina, Rainer, Johannes, Manke, Thomas, Schäfer, Georg, Pasqualini, Lorenza, Chines, Peter, Schweiger, Michal R., Fuchsberger, Christian, Klocker, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715509/
https://www.ncbi.nlm.nih.gov/pubmed/26411452
http://dx.doi.org/10.1002/humu.22909