Is the gene encoding Chibby implicated as a tumour suppressor in colorectal cancer ?

BACKGROUND: A novel member of the Wnt signalling pathway, Chibby, was recently identified. This protein inhibits Wnt/β-catenin mediated transcriptional activation by competing with Lef-1 (the transcription factor and target of β-catenin) to bind to β-catenin. This suggests that Chibby could be a tum...

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Detalles Bibliográficos
Autores principales: Gad, Sophie, Teboul, David, Lièvre, Astrid, Goasguen, Nicolas, Berger, Anne, Beaune, Philippe, Laurent-Puig, Pierre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC471554/
https://www.ncbi.nlm.nih.gov/pubmed/15245581
http://dx.doi.org/10.1186/1471-2407-4-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC471554/
https://www.ncbi.nlm.nih.gov/pubmed/15245581
http://dx.doi.org/10.1186/1471-2407-4-31

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