Cargando…
Is the gene encoding Chibby implicated as a tumour suppressor in colorectal cancer ?
BACKGROUND: A novel member of the Wnt signalling pathway, Chibby, was recently identified. This protein inhibits Wnt/β-catenin mediated transcriptional activation by competing with Lef-1 (the transcription factor and target of β-catenin) to bind to β-catenin. This suggests that Chibby could be a tum...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC471554/ https://www.ncbi.nlm.nih.gov/pubmed/15245581 http://dx.doi.org/10.1186/1471-2407-4-31 |