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Activity and Toxicity of Intravenous Erwinia Asparaginase Following Allergy to E. coli‐Derived Asparaginase in Children and Adolescents With Acute Lymphoblastic Leukemia

BACKGROUND: Erwinia asparaginase is antigenically distinct from E.coli‐derived asparaginase and may be used after E.coli‐derived asparaginase hypersensitivity. In a single‐arm, multicenter study, we evaluated nadir serum asparaginase activity (NSAA) and toxicity with intravenously administered aspar...

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Detalles Bibliográficos
Autores principales: Vrooman, Lynda M., Kirov, Ivan I., Dreyer, ZoAnn E., Kelly, Michael, Hijiya, Nobuko, Brown, Patrick, Drachtman, Richard A., Messinger, Yoav H., Ritchey, A. Kim, Hale, Gregory A., Maloney, Kelly, Lu, Yuan, Plourde, Paul V., Silverman, Lewis B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715717/
https://www.ncbi.nlm.nih.gov/pubmed/26376459
http://dx.doi.org/10.1002/pbc.25757