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ZD7288, a blocker of the HCN channel family, increases doubling time of mouse embryonic stem cells and modulates differentiation outcomes in a context-dependent manner

Pluripotent stem cells are the starting cell type of choice for the development of many cell-based regenerative therapies due to their rapid and unlimited proliferation and broad differentiation potential. The unique pluripotent cell cycle underlies both these properties. Hyperpolarization-activated...

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Detalles Bibliográficos
Autores principales: Omelyanenko, Anna, Sekyrova, Petra, Andäng, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715829/
https://www.ncbi.nlm.nih.gov/pubmed/26835223
http://dx.doi.org/10.1186/s40064-016-1678-7