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Epitope specificity determines cross‐protection of a SIT‐induced IgG(4) antibody
BACKGROUND: The calcium‐binding 2EF‐hand protein Phl p 7 from timothy grass pollen is a highly cross‐reactive pollen pan‐allergen that can induce severe clinical symptoms in allergic patients. Recently, a human monoclonal Phl p 7‐specific IgG(4) antibody (mAb102.1F10) was isolated from a patient who...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716291/ https://www.ncbi.nlm.nih.gov/pubmed/26221749 http://dx.doi.org/10.1111/all.12710 |