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Epitope specificity determines cross‐protection of a SIT‐induced IgG(4) antibody

BACKGROUND: The calcium‐binding 2EF‐hand protein Phl p 7 from timothy grass pollen is a highly cross‐reactive pollen pan‐allergen that can induce severe clinical symptoms in allergic patients. Recently, a human monoclonal Phl p 7‐specific IgG(4) antibody (mAb102.1F10) was isolated from a patient who...

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Detalles Bibliográficos
Autores principales:	Gadermaier, E., James, L. K., Shamji, M. H., Blatt, K., Fauland, K., Zieglmayer, P., Garmatiuk, T., Focke‐Tejkl, M., Villalba, M., Beavil, R., Keller, W., Valent, P., Durham, S. R., Gould, H. J., Flicker, S., Valenta, R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	ORIGINAL ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716291/ https://www.ncbi.nlm.nih.gov/pubmed/26221749 http://dx.doi.org/10.1111/all.12710

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