Cargando…

Sequence-function correlations and dynamics of ERG isoforms. ERG8 is the black sheep of the family

The transcription factor ERG is known to have divergent roles. On one hand, it acts as differentiation factor of endothelial cells. On the other hand, it has pathological roles in various cancers. Genomic analyses of the ERG gene show that it gives rise to several isoforms. However, functional diffe...

Descripción completa

Detalles Bibliográficos
Autores principales: Hoesel, Bastian, Malkani, Naila, Hochreiter, Bernhard, Basílio, José, Sughra, Kalsoom, Ilyas, Muhammad, Schmid, Johannes A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716293/
https://www.ncbi.nlm.nih.gov/pubmed/26554849
http://dx.doi.org/10.1016/j.bbamcr.2015.10.023