Preclinical Modeling of Tumor Growth and Angiogenesis Inhibition to Describe Pazopanib Clinical Effects in Renal Cell Carcinoma

The objective was to leverage tumor size data from preclinical experiments to propose a model of tumor growth and angiogenesis inhibition for the analysis of pazopanib efficacy in renal cell carcinoma (RCC) patients. We analyzed tumor data in mice with RCC CAKI‐2 cell line treated with pazopanib. Cl...

Descripción completa

Detalles Bibliográficos
Autores principales: Ouerdani, A, Struemper, H, Suttle, AB, Ouellet, D, Ribba, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716582/
https://www.ncbi.nlm.nih.gov/pubmed/26783502
http://dx.doi.org/10.1002/psp4.12001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716582/
https://www.ncbi.nlm.nih.gov/pubmed/26783502
http://dx.doi.org/10.1002/psp4.12001

Ejemplares similares