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The promise of γδ T cells and the γδ T cell receptor for cancer immunotherapy

γδ T cells form an important part of adaptive immune responses against infections and malignant transformation. The molecular targets of human γδ T cell receptors (TCRs) remain largely unknown, but recent studies have confirmed the recognition of phosphorylated prenyl metabolites, lipids in complex...

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Detalles Bibliográficos
Autores principales: Legut, Mateusz, Cole, David K, Sewell, Andrew K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716630/
https://www.ncbi.nlm.nih.gov/pubmed/25864915
http://dx.doi.org/10.1038/cmi.2015.28