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Asymmetric stem-cell division ensures sustained keratinocyte hyperproliferation in psoriatic skin lesions

Excessive expansion of the transit-amplifying (TA) cell compartment is a distinct morphological characteristic of psoriatic epidermal hyperplasia. In order to examine the activation of basal stem cells and how they replenish such an enlarged compartment of TA cells in psoriatic epidermis, we utilize...

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Detalles Bibliográficos
Autores principales: JIA, HAI-YAN, SHI, YING, LUO, LONG-FEI, JIANG, GUAN, ZHOU, QIONG, XU, SHI-ZHENG, LEI, TIE-CHI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716788/
https://www.ncbi.nlm.nih.gov/pubmed/26707630
http://dx.doi.org/10.3892/ijmm.2015.2445