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Inhibition of mTOR sensitizes breast cancer stem cells to radiation-induced repression of self-renewal through the regulation of MnSOD and Akt

The sensitization of breast cancer stem cells (BrCSCs) to the inhibitive effects of radiotherapy through adjuvant therapy which targets oncogenic pathways represents a prospective strategy for improving the effect of radiation in patients with triple-negative breast cancer (TNBC). Mammalian target o...

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Detalles Bibliográficos
Autores principales: LAI, YUANHUI, YU, XINPEI, LIN, XIAOHONG, HE, SHANYANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716789/
https://www.ncbi.nlm.nih.gov/pubmed/26707081
http://dx.doi.org/10.3892/ijmm.2015.2441