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IL-17 intensifies IFN-γ-induced NOS2 upregulation in RAW 264.7 cells by further activating STAT1 and NF-κB

Interleukin-17 (IL-17) is a signature cytokine of Th17 cells. Previous research has indicated that IL-17 plays a proinflammatory role by exacerbating interferon-γ (IFN-γ)-induced inflammation. However, prior to this study, it was not known whether inducible nitric oxide synthase (iNOS or NOS2), a si...

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Detalles Bibliográficos
Autores principales: GAO, QIYUE, LIU, YANG, WU, YAN, ZHAO, QIANG, WANG, LIJUN, GAO, SHANSHAN, WEN, WEN, ZHANG, WEIPING, GUO, NING, ZHOU, JUAN, YUAN, ZUYI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716793/
https://www.ncbi.nlm.nih.gov/pubmed/26677135
http://dx.doi.org/10.3892/ijmm.2015.2433