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Identification of Pol IV and RDR2-dependent precursors of 24 nt siRNAs guiding de novo DNA methylation in Arabidopsis

In Arabidopsis thaliana, abundant 24 nucleotide small interfering RNAs (24 nt siRNA) guide the cytosine methylation and silencing of transposons and a subset of genes. 24 nt siRNA biogenesis requires nuclear RNA polymerase IV (Pol IV), RNA-dependent RNA polymerase 2 (RDR2) and DICER-like 3 (DCL3). H...

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Detalles Bibliográficos
Autores principales: Blevins, Todd, Podicheti, Ram, Mishra, Vibhor, Marasco, Michelle, Wang, Jing, Rusch, Doug, Tang, Haixu, Pikaard, Craig S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716838/
https://www.ncbi.nlm.nih.gov/pubmed/26430765
http://dx.doi.org/10.7554/eLife.09591