Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation

T follicular helper cells (Tfh) are critical for the longevity and quality of antibody-mediated protection against infection. Yet few signaling pathways have been identified to be unique solely to Tfh development. ROQUIN is a post-transcriptional repressor of T cells, acting through its ROQ domain t...

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Detalles Bibliográficos
Autores principales: Ramiscal, Roybel R, Parish, Ian A, Lee-Young, Robert S, Babon, Jeffrey J, Blagih, Julianna, Pratama, Alvin, Martin, Jaime, Hawley, Naomi, Cappello, Jean Y, Nieto, Pablo F, Ellyard, Julia I, Kershaw, Nadia J, Sweet, Rebecca A, Goodnow, Christopher C, Jones, Russell G, Febbraio, Mark A, Vinuesa, Carola G, Athanasopoulos, Vicki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716841/
https://www.ncbi.nlm.nih.gov/pubmed/26496200
http://dx.doi.org/10.7554/eLife.08698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716841/
https://www.ncbi.nlm.nih.gov/pubmed/26496200
http://dx.doi.org/10.7554/eLife.08698

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