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Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci
Coeliac disease (CD) is a chronic immune-mediated disease triggered by the ingestion of gluten. It has an estimated prevalence of approximately 1% in European populations. Specific HLA-DQA1 and HLA-DQB1 alleles are established coeliac susceptibility genes and are required for the presentation of gli...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717209/ https://www.ncbi.nlm.nih.gov/pubmed/25920553 http://dx.doi.org/10.1038/ejhg.2015.87 |