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Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci

Coeliac disease (CD) is a chronic immune-mediated disease triggered by the ingestion of gluten. It has an estimated prevalence of approximately 1% in European populations. Specific HLA-DQA1 and HLA-DQB1 alleles are established coeliac susceptibility genes and are required for the presentation of gli...

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Detalles Bibliográficos
Autores principales:	Coleman, Ciara, Quinn, Emma M, Ryan, Anthony W, Conroy, Judith, Trimble, Valerie, Mahmud, Nasir, Kennedy, Nicholas, Corvin, Aiden P, Morris, Derek W, Donohoe, Gary, O'Morain, Colm, MacMathuna, Padraic, Byrnes, Valerie, Kiat, Clifford, Trynka, Gosia, Wijmenga, Cisca, Kelleher, Dermot, Ennis, Sean, Anney, Richard JL, McManus, Ross
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717209/ https://www.ncbi.nlm.nih.gov/pubmed/25920553 http://dx.doi.org/10.1038/ejhg.2015.87

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