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Regional metabolic heterogeneity of the hippocampus is nonuniformly impacted by age and caloric restriction

The hippocampus is critical for cognition and memory formation and is vulnerable to age‐related atrophy and loss of function. These phenotypes are attenuated by caloric restriction (CR), a dietary intervention that delays aging. Here, we show significant regional effects in hippocampal energy metabo...

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Detalles Bibliográficos
Autores principales: Martin, Stephen A., DeMuth, Tyler M., Miller, Karl N., Pugh, Thomas D., Polewski, Michael A., Colman, Ricki J., Eliceiri, Kevin W., Beasley, Timothy Mark, Johnson, Sterling C., Anderson, Rozalyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717265/
https://www.ncbi.nlm.nih.gov/pubmed/26521867
http://dx.doi.org/10.1111/acel.12418