Reduced in vivo hepatic proteome replacement rates but not cell proliferation rates predict maximum lifespan extension in mice

Combating the social and economic consequences of a growing elderly population will require the identification of interventions that slow the development of age‐related diseases. Preserved cellular homeostasis and delayed aging have been previously linked to reduced cell proliferation and protein sy...

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Detalles Bibliográficos
Autores principales: Thompson, Airlia C. S., Bruss, Matthew D., Price, John C., Khambatta, Cyrus F., Holmes, William E., Colangelo, Marc, Dalidd, Marcy, Roberts, Lindsay S., Astle, Clinton M., Harrison, David E., Hellerstein, Marc K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717272/
https://www.ncbi.nlm.nih.gov/pubmed/26541492
http://dx.doi.org/10.1111/acel.12414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717272/
https://www.ncbi.nlm.nih.gov/pubmed/26541492
http://dx.doi.org/10.1111/acel.12414

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