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Dissociation of somatic growth, time of sexual maturity, and life expectancy by overexpression of an RGD‐deficient IGFBP‐2 variant in female transgenic mice

Impaired growth is often associated with an extension of lifespan. However, the negative correlation between somatic growth and life expectancy is only true within, but not between, species. This can be observed because smaller species have, as a rule, a shorter lifespan than larger species. In inse...

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Detalles Bibliográficos
Autores principales: Hoeflich, Andreas, Reyer, Anja, Ohde, Daniela, Schindler, Nancy, Brenmoehl, Julia, Spitschak, Marion, Langhammer, Martina, Tuchscherer, Armin, Wirthgen, Elisa, Renner‐Müller, Ingrid, Wanke, Rüdiger, Metzger, Friedrich, Bielohuby, Maximilian, Wolf, Eckhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717279/
https://www.ncbi.nlm.nih.gov/pubmed/26507795
http://dx.doi.org/10.1111/acel.12413