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Dissociation of somatic growth, time of sexual maturity, and life expectancy by overexpression of an RGD‐deficient IGFBP‐2 variant in female transgenic mice
Impaired growth is often associated with an extension of lifespan. However, the negative correlation between somatic growth and life expectancy is only true within, but not between, species. This can be observed because smaller species have, as a rule, a shorter lifespan than larger species. In inse...
Autores principales: | Hoeflich, Andreas, Reyer, Anja, Ohde, Daniela, Schindler, Nancy, Brenmoehl, Julia, Spitschak, Marion, Langhammer, Martina, Tuchscherer, Armin, Wirthgen, Elisa, Renner‐Müller, Ingrid, Wanke, Rüdiger, Metzger, Friedrich, Bielohuby, Maximilian, Wolf, Eckhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717279/ https://www.ncbi.nlm.nih.gov/pubmed/26507795 http://dx.doi.org/10.1111/acel.12413 |
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