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Central insulin‐like growth factor‐1 (IGF‐1) restores whole‐body insulin action in a model of age‐related insulin resistance and IGF‐1 decline

Low insulin‐like growth factor‐1 (IGF‐1) signaling is associated with improved longevity, but is paradoxically linked with several age‐related diseases in humans. Insulin‐like growth factor‐1 has proven to be particularly beneficial to the brain, where it confers protection against features of neuro...

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Detalles Bibliográficos
Autores principales: Huffman, Derek M., Farias Quipildor, Gabriela, Mao, Kai, Zhang, Xueying, Wan, Junxiang, Apontes, Pasha, Cohen, Pinchas, Barzilai, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717281/
https://www.ncbi.nlm.nih.gov/pubmed/26534869
http://dx.doi.org/10.1111/acel.12415