A Rapid, Semi-Quantitative Assay to Screen for Modulators of Alpha-Synuclein Oligomerization Ex vivo

Alpha synuclein (αsyn) aggregates are associated with the pathogenesis of Parkinson's disease and others related disorders. Although modulation of αsyn aggregation is an attractive therapeutic target, new powerful methodologies are desperately needed to facilitate in vivo screening of novel the...

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Detalles Bibliográficos
Autores principales: Delenclos, Marion, Trendafilova, Teodora, Jones, Daryl R., Moussaud, Simon, Baine, Ann-Marie, Yue, Mei, Hirst, Warren D., McLean, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717311/
https://www.ncbi.nlm.nih.gov/pubmed/26834539
http://dx.doi.org/10.3389/fnins.2015.00511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717311/
https://www.ncbi.nlm.nih.gov/pubmed/26834539
http://dx.doi.org/10.3389/fnins.2015.00511

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