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HNF4α is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer

BACKGROUND: Worldwide, gastric cancer (GC) is the fourth most common malignancy and the most common cancer in East Asia. Development of targeted therapies for this disease has focused on a few known oncogenes but has had limited effects. OBJECTIVE: To determine oncogenic mechanisms and novel therape...

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Detalles Bibliográficos
Autores principales: Chang, Hae Ryung, Nam, Seungyoon, Kook, Myeong-Cherl, Kim, Kyung-Tae, Liu, Xiuping, Yao, Hui, Jung, Hae Rim, Lemos, Robert, Seo, Hye Hyun, Park, Hee Seo, Gim, Youme, Hong, Dongwan, Huh, Iksoo, Kim, Young-Woo, Tan, Dongfeng, Liu, Chang-Gong, Powis, Garth, Park, Taesung, Liang, Han, Kim, Yon Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717359/
https://www.ncbi.nlm.nih.gov/pubmed/25410163
http://dx.doi.org/10.1136/gutjnl-2014-307918